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Intrauterine insemination (IUI)

Inesminācija (IUI)

IUI stands for intrauterine insemination

Intrauterine insemination is an infertility treatment method where processed sperm of a man (the partner or a donor) is introduced into the uterine cavity of a woman.

The IUI procedure is carried out if the permeability of the Fallopian tubes of the female is normal, but natural insemination of an egg cell cannot be achieved due to sperm quality (as a result of low sperm motility and activity as well as due a low sperm count).

Intrauterine insemination is commonly combined with hormonal stimulation of the ovaries in order to achieve 1-2 mature egg cells in them. The IUI procedure is absolutely painless.

Step-by-Step IUI Procedure

1. First or repeated office visit to a fertility specialist (for a detailed medical history, identification of the potential reasons for infertility)

2. Professional medical advice + USG (transvaginal ultrasound – the structure of the uterus and the ovaries, any anatomic peculiarities etc.) + routine tests (blood and urine tests, swabs, spermogram) associated with the IUI procedure + the necessary medications

3. Procedure prior to IUI:

  • Hysterosalpingoscopy to assess the shape, size, any potential alterations and peculiarities of the uterine cavity as well as the permeability of the Fallopian tubes)
  • or hysteroscopy (an examination of the uterine cavity with an optical probe)
  • Blood tests: FSH and oestradiol levels, and others
  • Sperm analysis (evaluation of sperm count, structure and motility), function test
  • Blood tests (thyreotropic hormones, prolactin, blood group and rhesus factor as well as testing for contagious diseases, such as STDs (chlamydiosis, syphilis, HIV and others) etc.

4. Waiting for the start of a new natural menstruation or medically induced ovulation

5. A USG scan on Day 9-12 of the cycle (depending on the length of the menstrual cycle)

6. Induction of ovulation with an Ovitrelle or Pregnyl injection

7. The IUI procedure approximately on Day 13-15 of the cycle

8. Pharmacological therapy of at least 14 days to maintain the corpus luteum

9. Blood tests for HCG progesterone levels on Day 14 after the IUI

10. A pregnancy monitoring USG scan in 4 weeks


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