HLA (Human Leukocyte Antigen) is a human leukocyte antigen or a tissue compatibility antigen. Antigens are proteins found on the outside of all cells in human body. HLA are necessary for the body to be able to recognise foreign cells (bacteria, viruses, cancer cells, any donor material, etc.) and also to recognise its own cells and tissues. When HLA get into the body they trigger the immune response to destroy foreign cells. It is a protective mechanism of the body.
Usually HLA typing is used to establish donor/recipient match in transplantation.
In reproductive medicine, it means finding out whether the recipient and the egg donor are a match before fertilising the egg with a donor’s or partner’s sperm with consequent embryo implantation in the uterus. HLA typing of the recipient and egg donor is a new and unique method of testing in reproductive genetics.
iVF Riga Genetics Centre Lab offers HLA typing: https://genetikascentrs.lv/pakalpojumi/genetiskas-analizes/hla-tipesana/
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