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Intratesticular PRP injection

PRP therapy: An advanced female and male infertility treatment method

Only at iVF Riga!

Testicle PRP – for men it is an opportunity to activate sperm production (spermatogenesis) and become a biological father!

iVF Riga Andrology and Urology Centre works with all kinds of male infertility problems. Testicle PRP therapy is used for treatment of the most complex cases of male infertility:

  • semen contains very few sperm (oligozoospermia <10 million/ml);
  • hormonal therapy is not advisable;
  • failed hormonal therapy.

Normally in such cases chances of pregnancy are extremely low. The new, innovative treatment using testicle PRP therapy may offer a solution.

How is testicle PRP procedure done?

The PRP therapy (autologous platelet-rich plasma) is treatment using plasma obtained from the patient’s own blood and enriched with platelets (blood cells containing large quantities of alpha granules with high growth factor concentration). Growth factors play an important role because they ensure tissue generation and activate cell growth and restoration. Injections of high levels of platelet-rich plasma into damaged or atrophied tissue activate regenerative and restorative processes.

PRP therapy steps

PRP therapy consists of several steps. First, 8-20 ml of peripheral blood is taken from the patient. The blood is then placed into a centrifuge and centrifuged to break it into the components. Plasma with platelets is separated from the other blood cells. This method enables to obtain 3-5 times higher plasma platelet levels than normally in peripheral blood.

The purpose of the procedure is to activate spermatogenesis (sperm production), which is not active enough leading to the reduction the sperm quality and inability to conceive. After injection of platelet-rich plasma into testicular tissue, cell regeneration and repair is activated helping restore spermatogenesis.

Indications for testicle PRP therapy:

  1. oligozoospermia <10 million/ml
  2. FSH >10, normal or low testosterone level
  3. Testicular ultrasound – normal or diffusely changed echogenicity, patients with local foci/tumours or microcalcification are not included
  4. Negative tumour markers (LDH, alpha-fetoprotein, free hCG)
  5. Normal karyotype, negative Y chromosome microdeletions (oligozoospermia <5 million/ml)

Examinations necessary for PRP therapy

Before the procedure and in 3 and 6 months after the procedure, the following should be done:

  1. testicular ultrasound
  2. bloods for FSH, testosterone, LH, SHBG, LDH, alpha-fetoprotein, free hCG, full blood count;
  3. seminogram, sperm DNS integrity test, HBA test, Interleukin-6 in the semen;
  4. andrologist consultation.

This innovative procedure has emerged recently and is still experimental. That is why we cannot guarantee a positive outcome. However, it is known that PRP stimulates and restores cellular processes and PRP injections are used with great success for other conditions, such as arthritis and arthrosis (by injecting into joints), hair loss, female infertility (by injecting PRP into the ovaries or insufficiently active uterus lining, i.e. endometrium), etc. Moreover, according to the available data, in 50% of the cases in men who have been diagnosed with infertility the procedure was successful enough to enable retrieval of sperm during testicular biopsy to be used for artificial insemination.

The innovative PRP method enables men who have been diagnosed with infertility to father children.

Progressive medical specialists are confident that PRP therapy is a breakthrough in reproductive medicine and can give men a chance to have their biological children owing to restored spermatogenesis.

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