PRP means platelet-rich plasma obtained from human blood after special processing of a blood sample. Such platelet-rich plasma or PRP is an unique biological material obtained from each person, very rich in various growth factors and hormones, which causes the growth, development and regeneration of tissues and cells into which it is injected.
PRP injection is used with great success in various fields of medicine: in traumatology - for the healing of muscles, tendons, ligaments and other tissues or wounds; in orthopedics, PRP provides quick restoration of joint functions and reduces pain, so it is widely used in arthritis and other orthopedic diseases. PRP injections are widely used for cosmetological purposes - to achieve skin regeneration and rejuvenation, stimulate hair growth in case of hair loss, etc.
Treatment with PRP injections is gaining increasing use in the treatment of infertility. About 15% of couples experience infertility when pregnancy does not occur for more than a year, making it a common problem. The PRP procedure was first used to treat female infertility - it was found that PRP injections into the ovaries improve their activity and stimulate egg production in women with poor ovarian function, while in women with insufficient maturation of the inner layer of the uterus, so that it could successfully implant a fertilized egg, PRP injections can improve this function as well.
In turn, about half of the causes of infertility in couples is the so-called "male factor", or poor sperm quality. Sometimes the causes of poor sperm quality are easy enough to correct - these are harmful lifestyle factors (especially smoking and overweight), genital infections and inflammations, hormonal disorders. However, often in the practice of male infertility treatment, we are faced with a markedly reduced sperm quality, which is caused by poor testicular function - and such cases are becoming more and more relevant.
We observe that the testicles do not develop properly during male puberty due to some hereditary reasons, and as a result, in adulthood, the amount of sperm-producing cells in the testicles is reduced or they do not function fully. As a result, the number of sperm in the semen is reduced, moreover, they are of very low quality. It is in such cases, the PRP procedure for the testicles can be recommended - we obtain platelet-rich plasma from the patient's blood and inject it into the testicles. Once in the testicles, PRP promotes more active sperm-producing cells, makes them divide more actively, suppresses the processes of sperm death (known in biology as apoptosis), improving the quantity and quality of sperm.
The procedure is performed once, it is painless (performed under short-term intravenous anesthesia), and after the procedure, men do not feel any discomfort. Since the maturation process of each individual sperm cell lasts more than 2 months, after the procedure, the doctor will offer appropriate recommendations for further sperm quality improvement over the next 3 months (assessed for each patient individually), and the maximum effect on sperm quality is expected approximately 3 months after the procedure.
Testicular PRP injections may be recommended for couples who have failed medical insemination attempts or who are just planning medical insemination - to improve sperm quality before in vitro fertilization (IVF) procedures.